Structure of PDB 6wk0 Chain B

Receptor sequence
>6wk0B (length=311) Species: 9606 (Homo sapiens) [Search protein sequence]
EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAA
RLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIV
NNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEA
LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGS
AADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVD
TTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPY
KKDLPLTLFLE
3D structure
PDB6wk0 Crystal structures of human ribokinase
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.15: ribokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RIB B D27 G53 K54 N57 A109 E154 D269 D14 G40 K41 N44 A96 E141 D256
BS02 ACP B N199 T235 G237 A238 G240 T256 V259 A267 G268 N295 A298 A299 V302 N186 T222 G224 A225 G227 T243 V246 A254 G255 N282 A285 A286 V289
Gene Ontology
Molecular Function
GO:0004747 ribokinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006014 D-ribose metabolic process
GO:0006098 pentose-phosphate shunt
GO:0006753 nucleoside phosphate metabolic process
GO:0016310 phosphorylation
GO:0019303 D-ribose catabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wk0, PDBe:6wk0, PDBj:6wk0
PDBsum6wk0
PubMed
UniProtQ9H477|RBSK_HUMAN Ribokinase (Gene Name=RBKS)

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