Structure of PDB 6wi2 Chain B

Receptor sequence
>6wi2B (length=83) Species: 9606 (Homo sapiens) [Search protein sequence]
ASSRAQVLALYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEI
QTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIEN
3D structure
PDB6wi2 The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
ChainB
Resolution1.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 EDT B Y26 R29 Y24 R27
BS02 8Q1 B R6 V9 F40 N43 K44 V46 I52 L55 R4 V7 F38 N41 K42 V44 I50 L53
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0016226 iron-sulfur cluster assembly
GO:0044571 [2Fe-2S] cluster assembly
GO:0044572 [4Fe-4S] cluster assembly
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0016604 nuclear body
GO:0099128 mitochondrial [2Fe-2S] assembly complex
GO:1990221 L-cysteine desulfurase complex
GO:1990229 iron-sulfur cluster assembly complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6wi2, PDBe:6wi2, PDBj:6wi2
PDBsum6wi2
PubMed
UniProtQ9HD34|LYRM4_HUMAN LYR motif-containing protein 4 (Gene Name=LYRM4)

[Back to BioLiP]