Structure of PDB 6wh4 Chain B

Receptor sequence
>6wh4B (length=358) Species: 562,9606 [Search protein sequence]
LHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAI
ADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCA
ISLDRYVAIQSRTKAFLKIIAVWTISVGISMPIPVFGLQSKVFKEGSCLL
ADDNFVLIGSFVSFFIPATIMVITYFLTIKSLQKEAADLEDNWETLNDNL
KVIEKNAAQVKDALTKMRAAALDAQKASPEMKDFRHGFDILVGQIDDAAQ
AAAEQLKTTRNAYIQKYLTMQSISNEQKACKVLGIVFFLFVVMWCPFFIT
NIMAVICKESCNEDVIGALLNVFVWIGYASSAVNPLVYTLFNKTYRSAFS
RYIQCQYK
3D structure
PDB6wh4 Structure of a Hallucinogen-Activated Gq-Coupled 5-HT 2A Serotonin Receptor
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 89F B W151 D155 V156 S159 L229 V235 S242 W336 F340 N343 W83 D87 V88 S91 L150 V156 S163 W294 F298 N301
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0042597 periplasmic space

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Biological Process
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Cellular Component
External links
PDB RCSB:6wh4, PDBe:6wh4, PDBj:6wh4
PDBsum6wh4
PubMed
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P28223|5HT2A_HUMAN 5-hydroxytryptamine receptor 2A (Gene Name=HTR2A)

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