Structure of PDB 6w81 Chain B

Receptor sequence
>6w81B (length=300) Species: 28295 (Porcine epidemic diarrhea virus) [Search protein sequence]
AGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDTVICPRHVIASSTTST
IDYDYALSVLRLHNFSISSGNVFLGVVGVTMRGALLQIKVNQNNVHTPKY
TYRTVRPGESFNILACYDGSAAGVYGVNMRSNYTIRGSFINGACGSPGYN
INNGTVEFCYLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASSLFT
ENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMTTVVNTDCFSIL
AAKTGVDVQRLLASIQSLHKNFGGKQILGYTSLTDEFTTGEVIRQMYGVN
3D structure
PDB6w81 A taxonomically-driven approach to development of potent, broad-spectrum inhibitors of coronavirus main protease including SARS-CoV-2 (COVID-19)
ChainB
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 X77 B H41 T47 I140 N141 G142 C144 H162 Q163 L164 E165 P188 H41 T47 I140 N141 G142 C144 H162 Q163 L164 E165 P188
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

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Molecular Function

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Biological Process
External links
PDB RCSB:6w81, PDBe:6w81, PDBj:6w81
PDBsum6w81
PubMed
UniProtA0A059VJE6

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