Structure of PDB 6w3z Chain B

Receptor sequence
>6w3zB (length=333) Species: 6279 (Brugia malayi) [Search protein sequence]
STIIKGYDFNEGINYDALLDQYMSTGFQASHFAQAVQQINTMLTIREEQF
EGDHTLPYPEGKQKRACTIFLGYTSNLVTSGVRENIRYLVEHDLVDCIVT
SAGGVEEDLIKCLAPSYLGAFDLDGKTLRHNGLNRAGNIIIPNNNYCQFE
DWLMPILDSCELEQKNNDFSWTPSKLIDRLGAEINDKRSICYWAHRNRIP
VFSPALTDGSIGDMLYFHSFRNGGIKLDIVEDLRHINTMAVRSNRTGVIL
LGGGVMKHHINNANLMRNGSDYAVYVNTGQEFDGSDSGARPDEAVSWGKV
RSDCRPVKIYADATLVFPLLVAKTFARHVQQKH
3D structure
PDB6w3z Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B T102 S103 N104 S129 A130 G131 D236 G280 G281 N305 T306 D340 A341 T74 S75 N76 S101 A102 G103 D208 G252 G253 N277 T278 D312 A313
BS02 NAD B G282 H286 D311 S313 D314 S315 G254 H258 D283 S285 D286 S287
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0034038 deoxyhypusine synthase activity
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w3z, PDBe:6w3z, PDBj:6w3z
PDBsum6w3z
PubMed33044977
UniProtA0A0J9XTC4

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