Structure of PDB 6w18 Chain B

Receptor sequence
>6w18B (length=367) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
IVLDNGTGFVKVGYAKDNFPRFQFPSIVGRPIKDVMVGDEAEAVRSLLQV
KYPMENGIIRDFEEMNQLWDYTFFEKLKIDPRGRKILLTEPPMNPVANRE
KMCETMFERYGFGGVYVAIQAVLSLYAQGLSSGVVVDSGDGVTHIVPVYE
SVVLNHLVGRLDVAGRDATRYLISLLLRKGYAFNRTADFETVREMKEKLC
YVSYDLELDHKLSEETTVLMRNYTLPDGRVIKVGSERYECPECLFQPHLV
GSEQPGLSEFIFDTIQAADVDIRKYLYRAIVLSGGSSMYAGLPSRLEKEI
KQLWFERVLHGDPARLPNFKVKIEDAPRRRHAVFIGGAVLADIMAQNDHM
WVSKAEWEEYGVRALDK
3D structure
PDB6w18 Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state.
ChainB
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B T12 G156 D157 E214 T7 G139 D140 E197
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0000147 actin cortical patch assembly
GO:0006897 endocytosis
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0090135 actin filament branching
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
GO:0005938 cell cortex
GO:0030479 actin cortical patch
GO:0031097 medial cortex
GO:0051285 cell cortex of cell tip

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w18, PDBe:6w18, PDBj:6w18
PDBsum6w18
PubMed32839613
UniProtQ9UUJ1|ARP2_SCHPO Actin-related protein 2 (Gene Name=arp2)

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