Structure of PDB 6vwy Chain B

Receptor sequence

>6vwyB (length=625) Species: 882 (Nitratidesulfovibrio vulgaris str. Hildenborough) [Search protein sequence]

SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRN
CIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRD
LIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVT
ICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHM
GCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGV
LRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCT
GNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYH
TRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDI
PSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKI
RQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAA
VCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWY
SEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMV
EPDPVKAADMLEAHIVARRARLGLT

3D structure

PDB

6vwy The Solvent-Exposed Fe-S D-Cluster Contributes to Oxygen-Resistance inDesulfovibrio vulgarisNi-Fe Carbon Monoxide Dehydrogenase.

Chain

Resolution

1.83 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.2.7.4: anaerobic carbon-monoxide dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SF4	B	C42 G45 C50	C39 G42 C47
BS02	SF4	B	C51 N53 C54 M56 G57 C59 V73 C74 R84 M203	C48 N50 C51 M53 G54 C56 V70 C71 R81 M200
BS03	XCC	B	H266 C301 C302 C340 G447 C448 C478 C519 Y553 S554 K556	H263 C298 C299 C337 G444 C445 C475 C516 Y550 S551 K553
BS04	CUV	B	H266 C301 C302 C340 G447 C448 G477 C478 C519 S554 K556	H263 C298 C299 C337 G444 C445 G474 C475 C516 S551 K553

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0004601	peroxidase activity
GO:0016151	nickel cation binding
GO:0016491	oxidoreductase activity
GO:0043885	anaerobic carbon-monoxide dehydrogenase activity
GO:0046872	metal ion binding
GO:0050418	hydroxylamine reductase activity
GO:0051537	2 iron, 2 sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

	Biological Process
GO:0006091	generation of precursor metabolites and energy
GO:0042542	response to hydrogen peroxide
GO:0098869	cellular oxidant detoxification

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:6vwy, PDBe:6vwy, PDBj:6vwy
PDBsum	6vwy
PubMed	32655979
UniProt	Q72A99

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