Structure of PDB 6vqt Chain B

Receptor sequence

>6vqtB (length=584) Species: 279238 (Novosphingobium aromaticivorans DSM 12444)

DGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAV
DAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATR
HLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAP
TVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMN
RLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSENS
LGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRP
LDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFD
NVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPW
EGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASR
AEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVK
NPPILLFDEATSALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDT
ILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAA

3D structure

• PDB: 6vqt A structural framework for unidirectional transport by a bacterial ABC exporter.
• Chain: B
• Resolution: 3.03 Å

Enzymatic activity

• Enzyme Commision number: 7.-.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADP	B	K497 S499	K483 S485
BS02	ADP	B	Y370 R374 G397 G399 K400 S401 T402	Y356 R360 G383 G385 K386 S387 T388

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042626 ATPase-coupled transmembrane transporter activity
• GO:0140359 ABC-type transporter activity

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0046689 response to mercury ion
• GO:0055085 transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:6vqt, PDBe:6vqt, PDBj:6vqt
• PDBsum: 6vqt
• PubMed: 32703810
• UniProt: Q2G506|ATM1_NOVAD ATM1-type heavy metal exporter (Gene Name=atm1)