Structure of PDB 6vou Chain B

Receptor sequence
>6vouB (length=174) Species: 588 (Providencia stuartii) [Search protein sequence]
GIEYRSLHTSQLTLSEKEALYDLLIEGFEGDFSHDDFAHTLGGMHVMAFD
QQKLVGHVAIIQRHMALDNTPISVGYVEAMVVEQSYRRQGIGRQLMLQTN
KIIASCYQLGLLSASGQKLYHSVGWQIWKGKLFELKQGSYIRSIEEEGGV
MGWKADEVDFTASLYCDFRGGDQW
3D structure
PDB6vou Structural basis for plazomicin antibiotic action and resistance.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.59: gentamicin 2'-N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA B F29 M81 V82 V83 R88 R89 Q90 G91 G93 R94 S116 Y123 F28 M80 V81 V82 R87 R88 Q89 G90 G92 R93 S115 Y120
BS02 PZC B D32 D37 A80 S114 A115 S116 E148 E149 D176 W178 D31 D36 A79 S113 A114 S115 E145 E146 D172 W174
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0047921 aminoglycoside 2'-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:6vou, PDBe:6vou, PDBj:6vou
PDBsum6vou
PubMed34117352
UniProtQ52424|AAC2_PROST Aminoglycoside 2'-N-acetyltransferase (Gene Name=aac)

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