Structure of PDB 6vld Chain B

Receptor sequence
>6vldB (length=469) Species: 9606 (Homo sapiens) [Search protein sequence]
GLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDL
GHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWE
TVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPL
AVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFK
HPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYL
ATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHF
LSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHN
QIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSY
KVREKIETVKYPTYPEAEK
3D structure
PDB6vld Structural basis of substrate recognition and catalysis by fucosyltransferase 8.
ChainB
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.68: glycoprotein 6-alpha-L-fucosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B Y220 G221 Y250 H363 R365 K369 A407 T408 A436 R441 V450 D453 S469 Q470 V471 Y114 G115 Y144 H257 R259 K263 A301 T302 A330 R335 V344 D347 S363 Q364 V365
External links
PDB RCSB:6vld, PDBe:6vld, PDBj:6vld
PDBsum6vld
PubMed32220931
UniProtQ9BYC5|FUT8_HUMAN Alpha-(1,6)-fucosyltransferase (Gene Name=FUT8)

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