Structure of PDB 6vgh Chain B

Receptor sequence
>6vghB (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSLTADQMVSALLDAEPPILYSEYDPTRPFSMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKSVEMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSVPLSDLLLEMLD
3D structure
PDB6vgh Ligand Binding Domain
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C3D B L346 A350 D351 E353 W383 L384 L525 L37 A41 D42 E44 W74 L75 L213 BindingDB: IC50=4nM,EC50=3.1nM
External links
PDB RCSB:6vgh, PDBe:6vgh, PDBj:6vgh
PDBsum6vgh
PubMed
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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