Structure of PDB 6v3c Chain B

Receptor sequence
>6v3cB (length=260) Species: 10090 (Mus musculus) [Search protein sequence]
SAINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREK
FLRAHPCVSDQELDELIQQIVAADPLGASSNQVSHWDLGSSFFFAGTVIT
TIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAQ
TKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIG
FGDYVAGGSDLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIAKKTKEA
VGEFRAHAAE
3D structure
PDB6v3c Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
ChainB
Resolution3.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K B T142 I143 T251 I252 T101 I102 T198 I199
BS02 K B I143 G144 F145 I252 G253 I102 G103 F104 I199 G200
BS03 K B T142 T251 T101 T198
BS04 K B G144 F145 G146 G253 F254 G255 G103 F104 G105 G200 F201 G202
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6v3c, PDBe:6v3c, PDBj:6v3c
PDBsum6v3c
PubMed32059793
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

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