Structure of PDB 6v1b Chain B

Receptor sequence
>6v1bB (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SKERLLALKRSMS
3D structure
PDB6v1b Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainB
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 H1B B F160 F161 V165 I169 Y215 N216 R217 T220 Y222 F23 F24 V28 I32 Y78 N79 R80 T83 Y85 MOAD: Kd=37nM
External links
PDB RCSB:6v1b, PDBe:6v1b, PDBj:6v1b
PDBsum6v1b
PubMed32091206
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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