Structure of PDB 6v17 Chain B

Receptor sequence
>6v17B (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]
EQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTM
KEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKI
LSQERIQSLKQSIDFMADL
3D structure
PDB6v17 Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 H1B B F155 F156 I164 A165 Y210 N211 K212 T215 Y217 F24 F25 I33 A34 Y79 N80 K81 T84 Y86 MOAD: Kd=148nM
External links
PDB RCSB:6v17, PDBe:6v17, PDBj:6v17
PDBsum6v17
PubMed32091206
UniProtQ9NPI1|BRD7_HUMAN Bromodomain-containing protein 7 (Gene Name=BRD7)

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