Structure of PDB 6v16 Chain B

Receptor sequence
>6v16B (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
LQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKI
KNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQE
RIQSLKQSI
3D structure
PDB6v16 Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QMG B F155 V160 I164 N211 Y217 F20 V25 I29 N76 Y82 MOAD: Kd=556nM
BindingDB: Kd=556nM
External links
PDB RCSB:6v16, PDBe:6v16, PDBj:6v16
PDBsum6v16
PubMed32091206
UniProtQ9NPI1|BRD7_HUMAN Bromodomain-containing protein 7 (Gene Name=BRD7)

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