Structure of PDB 6v0a Chain B

Receptor sequence

>6v0aB (length=444) Species: 398767 (Trichlorobacter lovleyi SZ)

IPDGTIDPAVWGKNYPEEYQTWKDTALPTPEGKSKYKKGNDGGKVYDKLS
EYPFIALLFNGWGFGIEYNEPRGHVYMMKDQKEIDPSRLKGGGACLTCKT
PYAPQLAQKQGVTYFSQSYADAVNQIPKEHQEMGVACIDCHNNKDMGLKI
SRGFTLVKALDKMGVDQTKLTNQDKRSLVCAQCHVTYTIPKDANMKSQDV
FFPWDESKWGKISIENIIKKMRSDKSYGEWTQAVTGFKMAYIRHPEFEMY
SNQSVHWMAGVSCADCHMPYTKGSKKISDHRIMSPLKNDFKGCKQCHSES
SEWLKNQVITIQDRAASQYIRSGYALATVAKLFEMTHKQQAAGKQIDQKM
YDQAKFYYEEGFYRNLFFGAENSIGFHNPTEAMRILGDATMYAGKADGLL
RQALTKAGVDVPVKIDLELSKYTNNRGAKKLMFKPEQELKDPYG

3D structure

• PDB: 6v0a Cytochromecnitrite reductase from the bacteriumGeobacter lovleyirepresents a new NrfA subclass.
• Chain: B
• Resolution: 2.55 Å

Enzymatic activity

• Enzyme Commision number: 1.7.2.2: nitrite reductase (cytochrome; ammonia-forming).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	B	N103 Q115 I118 R122 C129 C132 K133 C217 H218 Y221 H278 N407	N69 Q81 I84 R88 C95 C98 K99 C183 H184 Y187 H244 N372
BS02	HEC	B	Y49 E52 W56 A170 C171 C174 H175 M180 L182 R210 M302 K311 I312 S313 H315	Y15 E18 W22 A136 C137 C140 H141 M146 L148 R176 M268 K276 I277 S278 H280
BS03	HEC	B	P105 R106 H108 Y110 M111 D114 C132 K133 V213 C214 C217 H218 H301 I317	P71 R72 H74 Y76 M77 D80 C98 K99 V179 C180 C183 H184 H267 I282
BS04	HEC	B	S68 K71 H218 E280 Y284 H290 S296 C297 C300 H301 S319 P320 L321 Q347 N407 F411 H412	S34 K37 H184 E246 Y250 H256 S262 C263 C266 H267 S284 P285 L286 Q312 N372 F376 H377
BS05	HEC	B	H290 D299 C300 C328 C331 H332 L339 F411	H256 D265 C266 C293 C296 H297 L304 F376

Gene Ontology

Molecular Function

• GO:0042279 nitrite reductase (cytochrome, ammonia-forming) activity

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:6v0a, PDBe:6v0a, PDBj:6v0a
• PDBsum: 6v0a
• PubMed: 32518164
• UniProt: B3E641