Structure of PDB 6uzy Chain B

Receptor sequence
>6uzyB (length=278) Species: 8364 (Xenopus tropicalis) [Search protein sequence]
YKGLRLELAVDKLVSCIAVGLPLLLISLAFAQEITLGSQISCFAPTSFSW
RQAAYVDSFCWAALWLHKFFPYILLLVAVLLYLPNLFWRFTAAPHLSSDL
KFVMEELDKCYNRDIKDIKAAPIVEQYLKTKNNSYGLIIKYLICRVVTLI
IVFTACIYLGYYISLFSLTDEFTCNIRTGILRNDTALPPLVQCKLIAVGV
FRLLSYINLIIYVLIMPFIIYAMLVPFRKTANVLKVYEVLPTFSKTYDDH
SLFLLFLEENVSELKSYKFLKVLENIKN
3D structure
PDB6uzy Cryo-EM structures of the ATP release channel pannexin 1.
ChainB
Resolution3.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6OU B L37 I41 F292 Y295 R302 L13 I17 F218 Y221 R228
Gene Ontology
Molecular Function
GO:0015267 channel activity
GO:0042802 identical protein binding
Biological Process
GO:0006812 monoatomic cation transport
GO:0032732 positive regulation of interleukin-1 production
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6uzy, PDBe:6uzy, PDBj:6uzy
PDBsum6uzy
PubMed32231289
UniProtB3DLA5

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