Structure of PDB 6uvc Chain B

Receptor sequence
>6uvcB (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAF
SDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESV
DKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN
3D structure
PDB6uvc Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X L and BCL-2.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XOY B F97 Y101 F105 L108 L130 W137 G138 R139 A142 F42 Y46 F50 L53 L75 W82 G83 R84 A87
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:6uvc, PDBe:6uvc, PDBj:6uvc
PDBsum6uvc
PubMed33904752
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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