Structure of PDB 6uuy Chain B

Receptor sequence
>6uuyB (length=246) Species: 6185 (Schistosoma haematobium) [Search protein sequence]
TTIQVIGAGLPRTGTNSMKKALEIIYSKPCYHMYEIIFKKQSDISIWQQL
IDETHKTTSDKRKIYNGLNELLNGYIATTDLPSCSFYKELMTMYPNAKVL
LTIRDKYDWLYSLRKVVLPKSTDPWKLKIEEGDQVLGIDSNFYKMSEDSL
KFAFQKNHINLDDDEILLECYDEYNRLVQEIVPPERLLIHHLGDGWESLC
QFLNVDIPNGISYPCANSHHQMTQLTEQLIKHKSLDDIIHMFPGLI
3D structure
PDB6uuy Molecular basis for hycanthone drug action in schistosome parasites.
ChainB
Resolution1.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3P B R32 G34 T35 N36 S37 R124 S132 L212 C235 N237 S238 H239 R12 G14 T15 N16 S17 R104 S112 L192 C215 N217 S218 H219
BS02 QHM B M53 D100 V137 D153 F162 Y163 S166 M33 D80 V117 D133 F142 Y143 S146 MOAD: Kd=2.5uM
BS03 CA B E185 E189 E165 E169
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6uuy, PDBe:6uuy, PDBj:6uuy
PDBsum6uuy
PubMed32027942
UniProtA0A094ZWQ2

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