Structure of PDB 6ust Chain B

Receptor sequence
>6ustB (length=463) Species: 154046 (Hungatella hathewayi) [Search protein sequence]
PNFLFIFMDDMGWRDLACTGSTFYETPNIDRLCRQGMVFANSYASCPVCS
PSRASYLTGQYPARLGVTDWIDMEGTSHPLRGKLIDAPYIKHLPEGEYTI
AQALKDAGYETWHVGKWHLGGREYYPDHFGFDVNIGGCSWGHPHEGYFSP
YGIETLPEGPEGEYLTDRITDEAVRLLKERKAGGSRKPFYMNLCHYAVHT
PIQVKDEDRERFEKKAREQGLDQETALVEGEFHHTEDKKGRRVVRRVIQS
DPSYAGMIWNLDQNIGRLLEALSECGEEENTVVVFTSDNGGLATSEGSPT
CNLPASEGKGWVYEGGTRVPLIVKYPGHVAPGSRCDVPVTTPDFYPTFLE
LAGVPQKSGIPIDGRSIVPLLAGNHMPERPVFWHYPHYGNQGGTPAASVV
LGDYKYIEFFEDGRGELYDLKADFSETNNICENMPEMAARLRMLLHGWQR
EVCARFPEVNEAY
3D structure
PDB6ust Structural Insights into Endobiotic Reactivation by Human Gut Microbiome-Encoded Sulfatases.
ChainB
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D13 D14 C53 R57 K120 H122 G145 H203 D292 N293 K313
Catalytic site (residue number reindexed from 1) D9 D10 C49 R53 K116 H118 G141 H199 D288 N289 K309
Enzyme Commision number 3.1.6.1: arylsulfatase (type I).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D13 D14 C53 D292 N293 D9 D10 C49 D288 N289
Gene Ontology
Molecular Function
GO:0004065 arylsulfatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6ust, PDBe:6ust, PDBj:6ust
PDBsum6ust
PubMed32993284
UniProtA0A174CV66

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