Structure of PDB 6uqf Chain B

Receptor sequence
>6uqfB (length=531) Species: 9606 (Homo sapiens) [Search protein sequence]
MQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRF
YWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVCLLDLIMN
FRTGTVNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVERAL
RIVRFTKILCLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGM
MLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMS
HMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSR
RQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELN
DPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIR
EGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVR
ADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQK
FQKDLNTGVFNNQENEILKQIVKHDREMVQA
3D structure
PDB6uqf Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
ChainB
Resolution3.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP B M530 F538 G539 E540 I541 C542 R549 T550 A551 R593 I594 M426 F434 G435 E436 I437 C438 R445 T446 A447 R489 I490
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6uqf, PDBe:6uqf, PDBj:6uqf
PDBsum6uqf
PubMed31787376
UniProtO60741|HCN1_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Gene Name=HCN1)

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