Structure of PDB 6u8g Chain B

Receptor sequence
>6u8gB (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTE
3D structure
PDB6u8g Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainB
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B F83 V87 L94 I100 I138 Y139 N140 K141 D144 F42 V46 L53 I59 I97 Y98 N99 K100 D103
External links
PDB RCSB:6u8g, PDBe:6u8g, PDBj:6u8g
PDBsum6u8g
PubMed33046654
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

[Back to BioLiP]