Structure of PDB 6u61 Chain B

Receptor sequence
>6u61B (length=117) Species: 9606 (Homo sapiens) [Search protein sequence]
KPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQP
MDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLE
KIFLQKVASMPQEEQEL
3D structure
PDB6u61 Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainB
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W97 F99 V103 L108 N156 D161 I162 W27 F29 V33 L38 N86 D91 I92
BS02 ZN B H83 E131 H13 E61
External links
PDB RCSB:6u61, PDBe:6u61, PDBj:6u61
PDBsum6u61
PubMed33046654
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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