Structure of PDB 6twk Chain B

Receptor sequence
>6twkB (length=396) Species: 2746 (Halomonas elongata) [Search protein sequence]
VSLPFTREEYAGRLWKVRTEMASRGIDVLVISDPSNMAWLTGYDGWSFYV
HQCVLLGLEGEPVWYGRRMDANGALRTCWMDPDNITYYPDHYVQNPDMHP
MDYLAQTILPDRGWHEGVVGMEMDNYYFSAKAYQCLLRELPHARFADANS
LVNWCRAIKSPQEIEYMRVAGKIVAGMHSRILEVIEPGLPKSKLVSEIYR
VGIEGWTSPEGKVFGGDYPAIVPMLPTGKDAAAPHLTWDDSPFREGEGTF
FEIAGVYKRYHAPMSRTVYLGRPPSEFVRAESALLEGIENGLEVAKPGNR
TADIAMALGAAMDKYGFDRGGARCGYPIGISYPPDWGERTMSLRPSDETI
LEPGMTFHFMPGLWVEDWGLEITESILITESGCETLADFPRQLFVK
3D structure
PDB6twk Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex.
ChainB
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.44: ectoine hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P4B B Y52 R70 Y49 R67
BS02 4CS B R326 Y329 D338 R323 Y326 D335
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Biological Process
GO:0042400 ectoine catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6twk, PDBe:6twk, PDBj:6twk
PDBsum6twk
PubMed32404365
UniProtE1V7W1|DOEA_HALED Ectoine hydrolase (Gene Name=doeA)

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