Structure of PDB 6tkv Chain B

Receptor sequence
>6tkvB (length=453) Species: 9606 (Homo sapiens) [Search protein sequence]
LGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLG
HHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKA
KKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWET
VFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLA
VPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKH
PVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLA
TDDPSLLKEAKTKYPNYEFISDNSLRGVILDIHFLSQADFLVCTFSSQVC
RVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIP
MEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPE
AEK
3D structure
PDB6tkv Structural basis for substrate specificity and catalysis of alpha 1,6-fucosyltransferase.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.68: glycoprotein 6-alpha-L-fucosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B G219 Y220 G221 C222 H363 R365 A407 T408 V450 D453 S469 Q470 G112 Y113 G114 C115 H256 R258 A300 T301 V328 D331 S347 Q348
External links
PDB RCSB:6tkv, PDBe:6tkv, PDBj:6tkv
PDBsum6tkv
PubMed32080177
UniProtQ9BYC5|FUT8_HUMAN Alpha-(1,6)-fucosyltransferase (Gene Name=FUT8)

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