Structure of PDB 6tiy Chain B

Receptor sequence
>6tiyB (length=430) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MREIVHIQAGQCGNQIGAKFWEIISDEHGIDATGAYHGDSDLQLERINVY
YNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
LISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADL
RKLAVNMVPFPRLHFFMPGFAPLTSRGSYRALTVPELTQQMFDAKNMMAA
CDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEWIPNNVKTA
VCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEG
MDEMEFTEAESNMNDLVSEYQQYQEATADE
3D structure
PDB6tiy GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation.
ChainB
Resolution2.293 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G2P B G10 Q11 C12 Q15 A97 N99 S138 G141 G142 T143 G144 P171 E181 N204 Y222 N226 G10 Q11 C12 Q15 A97 N99 S138 G141 G142 T143 G144 P171 E181 N204 Y222 N226
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tiy, PDBe:6tiy, PDBj:6tiy
PDBsum6tiy
PubMed33544140
UniProtQ24560|TBB1_DROME Tubulin beta-1 chain (Gene Name=betaTub56D)

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