Structure of PDB 6ted Chain B

Receptor sequence
>6tedB (length=1122) Species: 9823 (Sus scrofa) [Search protein sequence]
EITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPI
DLPPRYLLKFEQIYLSKPTHWEDGAPSPMMPNEARLRNLTYSAPLYVDIT
KTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPL
DPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSS
RPTSTIWVSMLARIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHI
IYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKY
AKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHY
GNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTR
IISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSP
IGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQP
SPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLR
KLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKR
HIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVA
YCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYIT
NFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGY
NQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQ
GMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLTKRDCSTFLRTSETG
IVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQE
DMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPF
NDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLK
HMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQF
LRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQISLVRMP
YACKLLFQELMSMSIAPRMMSV
3D structure
PDB6ted Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B D492 F823 D454 F785
BS02 rna B K934 K942 H1053 R1080 K882 K890 H1001 R1028
BS03 dna B R1078 R1085 R1026 R1033
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0003968 RNA-dependent RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ted, PDBe:6ted, PDBj:6ted
PDBsum6ted
PubMed32541898
UniProtI3LGP4

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