Structure of PDB 6t6f Chain B

Receptor sequence
>6t6fB (length=286) Species: 9606 (Homo sapiens) [Search protein sequence]
WKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKG
KESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIV
EKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKI
MISDFGPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSK
LFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPW
IAGDTALNKNIHESVSAQIRKNFAKMRKLHLGSSLD
3D structure
PDB6t6f CAMK1D bound to CS275
ChainB
Resolution1.97 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D144 K146 N149 D165
Catalytic site (residue number reindexed from 1) D133 K135 N138 D154
Enzyme Commision number 2.7.11.17: calcium/calmodulin-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MMW B L29 V37 A50 Q99 L100 V101 S102 E148 N149 L151 S164 D165 L18 V26 A39 Q88 L89 V90 S91 E137 N138 L140 S153 D154
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6t6f, PDBe:6t6f, PDBj:6t6f
PDBsum6t6f
PubMed
UniProtQ8IU85|KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D (Gene Name=CAMK1D)

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