Structure of PDB 6t2b Chain B

Receptor sequence
>6t2bB (length=439) Species: 239935 (Akkermansia muciniphila) [Search protein sequence]
AVEIPAGDHLWKSAPRPSGSTYMGGFKAPRLGRIRLAFIGVGGRGFSHLA
QMCVMDGVEIVGICDLKEELTKRGVDRVLSRMGKSPLGYSGGDMEYLTML
KELKPDAVIISTDWSSHARIACDSMKHGAHAFVEVPLAVSLEELWSLVDT
SEATRKHCMMMENVNYGRDELMFLNMVRQGVIGDLLHGEAAYIHCLVTQL
GDTRGEGAWRPEYHTRINGNLYPTHGLGPVAQYMNLERGEDRFCRVAAFA
SPALGRNAYAKKHLPADHRWNNTPFICGDMNTAVVKTQLGRTILVQLDET
SPRPYSRANLIQGTEGTLAGFPTRVAGEKLGNGNYHEWIEGREKLAAIYE
KYDHPLWKRIGELATKMGGHGGMDFVMLSRIVECLRNGEPMDQNVYEGAS
WSSLLPLTARSIAQGGMPVEFPDFTRGDWKTTMPLAVVS
3D structure
PDB6t2b The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable alpha-Retaining and beta-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia muciniphila
ChainB
Resolution2.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G74 G77 R78 D99 L100 D127 S145 T146 W148 H151 E168 V169 N197 G239 E240 W243 Y256 H259 H404 G40 G43 R44 D65 L66 D93 S111 T112 W114 H117 E134 V135 N163 G205 E206 W209 Y222 H225 H370
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:6t2b, PDBe:6t2b, PDBj:6t2b
PDBsum6t2b
PubMed
UniProtB2UQL7|G1092_AKKM8 Glycosyl hydrolase family 109 protein 2 (Gene Name=Amuc_0920)

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