Structure of PDB 6t12 Chain B

Receptor sequence
>6t12B (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB6t12 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainB
Resolution1.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M78 B S378 L380 W428 M434 L439 S35 L37 W85 M91 L96 MOAD: ic50=825uM
Gene Ontology

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Molecular Function
External links
PDB RCSB:6t12, PDBe:6t12, PDBj:6t12
PDBsum6t12
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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