Structure of PDB 6t10 Chain B

Receptor sequence
>6t10B (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLGGVFKIDWICRRE
LPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQ
VIHKM
3D structure
PDB6t10 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainB
Resolution1.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M6Z B W377 S378 W428 D476 W34 S35 W85 D124 MOAD: ic50=348uM
Gene Ontology

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Molecular Function
External links
PDB RCSB:6t10, PDBe:6t10, PDBj:6t10
PDBsum6t10
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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