Structure of PDB 6t0c Chain B

Receptor sequence
>6t0cB (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKGGVFKI
DWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPD
ESIDLYQVIHKM
3D structure
PDB6t0c Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainB
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M4E B W377 S378 W428 D476 W34 S35 W85 D131 MOAD: Kd=22uM
Gene Ontology

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Molecular Function
External links
PDB RCSB:6t0c, PDBe:6t0c, PDBj:6t0c
PDBsum6t0c
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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