Structure of PDB 6t06 Chain B

Receptor sequence
>6t06B (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB6t06 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M5H B N367 W377 S378 W428 M434 L439 N24 W34 S35 W85 M91 L96 MOAD: ic50=2010uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6t06, PDBe:6t06, PDBj:6t06
PDBsum6t06
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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