Structure of PDB 6t02 Chain B

Receptor sequence
>6t02B (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB6t02 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainB
Resolution1.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 M5E B W377 S378 T379 L380 W428 M434 W34 S35 T36 L37 W85 M91 MOAD: ic50>1000uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6t02, PDBe:6t02, PDBj:6t02
PDBsum6t02
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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