Structure of PDB 6szt Chain B

Receptor sequence
>6sztB (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB6szt Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M4Q B K361 N363 W377 S378 T379 L380 R404 W428 L430 M434 L439 D476 K18 N20 W34 S35 T36 L37 R61 W85 L87 M91 L96 D133 MOAD: ic50=1926uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6szt, PDBe:6szt, PDBj:6szt
PDBsum6szt
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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