Structure of PDB 6szr Chain B

Receptor sequence
>6szrB (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB6szr Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainB
Resolution1.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 M3Z B K361 W377 T379 R404 W428 P431 M434 D476 K18 W34 T36 R61 W85 P88 M91 D133 MOAD: ic50>1000uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6szr, PDBe:6szr, PDBj:6szr
PDBsum6szr
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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