Structure of PDB 6s6j Chain B

Receptor sequence
>6s6jB (length=209) Species: 9606 (Homo sapiens) [Search protein sequence]
WQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQPPLESVDVRQI
YDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWSSGGFYGVSSQYESLE
HMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFL
HKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGA
QHHIYRLVR
3D structure
PDB6s6j Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KXH B S349 V354 Y382 F386 S112 V117 Y145 F149
External links
PDB RCSB:6s6j, PDBe:6s6j, PDBj:6s6j
PDBsum6s6j
PubMed34509860
UniProtQ15562|TEAD2_HUMAN Transcriptional enhancer factor TEF-4 (Gene Name=TEAD2)

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