Structure of PDB 6s66 Chain B

Receptor sequence
>6s66B (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
WQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQPPLESVDVRQI
YDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWSGGFYGVSSQYESLEH
MTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLH
KLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQ
HHIYRLVR
3D structure
PDB6s66 Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KWW B S349 F350 V354 Y382 S111 F112 V116 Y144
External links
PDB RCSB:6s66, PDBe:6s66, PDBj:6s66
PDBsum6s66
PubMed34509860
UniProtQ15562|TEAD2_HUMAN Transcriptional enhancer factor TEF-4 (Gene Name=TEAD2)

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