Structure of PDB 6s3n Chain B

Receptor sequence

>6s3nB (length=436) Species: 56957 (Thermus oshimai) [Search protein sequence]

GLSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLA
PTGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQME
VLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPV
VPGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAEL
LKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLEA
LPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGD
LGWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVYTYDSEREEIKPQVVG
TFRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRL
QDLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKSH

3D structure

PDB

6s3n Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.

Chain

Resolution

2.533 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	P117 T118 G119 T129 H131 A138 V216 R302 R303 N356 N364 W396 H432 K433 R448 F451	P51 T52 G53 T63 H65 A72 V150 R236 R237 N290 N298 W330 H366 K367 R382 F385
BS02	ADP	B	L68 Q72 G94 T95 G96 K97 T99 Q255 R256 R258	L2 Q6 G28 T29 G30 K31 T33 Q189 R190 R192
BS03	MG	B	T98 D171	T32 D105

Gene Ontology

	Molecular Function
GO:0003678	DNA helicase activity
GO:0016887	ATP hydrolysis activity

	Biological Process
GO:0000723	telomere maintenance
GO:0006281	DNA repair

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Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:6s3n, PDBe:6s3n, PDBj:6s3n
PDBsum	6s3n
PubMed	33784404
UniProt	K7RJ88

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