Structure of PDB 6s2g Chain B

Receptor sequence

>6s2gB (length=624)

CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGS
IHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDI
RGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDD
GASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSIT
NATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESY
GEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQ
NHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSV
GWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWS
TKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTP
FSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLT
VVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYAN
DEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPAR
PANTSQGLVWDGPTAAMYGLFAGY

3D structure

• PDB: 6s2g Deciphering the molecular specificity of phenolic compounds as inhibitors or glycosyl acceptors of beta-fructofuranosidase from Xanthophyllomyces dendrorhous.
• Chain: B
• Resolution: 2.03 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FRU	B	N79 Q97 W105 F145 D146 R220 D221 E303 Y376	N38 Q56 W64 F104 D105 R179 D180 E262 Y335
BS02	KDH	B	N79 W105 E334 Q341 H343 L661	N38 W64 E293 Q300 H302 L620
BS03	KDH	B	K151 Q226 P228 H247 W317 P382 E384	K110 Q185 P187 H206 W276 P341 E343
BS04	KDH	B	K288 Q335 R337 A338 N342	K247 Q294 R296 A297 N301
BS05	KDH	B	P312 T324 V423 E425 T452	P271 T283 V382 E384 T411
BS06	KDH	B	T476 L477 A478 P479 G627 E629	T435 L436 A437 P438 G586 E588
BS07	KDH	B	A640 P642 T645	A599 P601 T604

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

Biological Process

• GO:0005975 carbohydrate metabolic process

External links

• PDB: RCSB:6s2g, PDBe:6s2g, PDBj:6s2g
• PDBsum: 6s2g
• PubMed: 31767902
• UniProt: J7HDY4