Structure of PDB 6rwm Chain B

Receptor sequence
>6rwmB (length=252) Species: 11723 (Simian immunodeficiency virus) [Search protein sequence]
FLDGIEKAQEEHEKYHNNWRAMAEDFQIPQVVAKEIVAQCPKCQSPKTWQ
MDCTHLEGKVIIVAVHVASGYIEAEVLPAETGKETAHFLLKLAARWPVKH
LHTDNGDNFTSSAVQAVCWWAQIEHTFGVVESMNHQLKTIITQIRDQAEK
IETAVQMAVLIHNFKRKGGIGGYSAGERIIDIIASDLQTTKLQNQISKIQ
NFRVYFREGRDQQWKGPATLIWKGEGAVVIQDGQDLKVVPRRKCKIIKDY
GR
3D structure
PDB6rwm Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
ChainB
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H12 H16 C40 H12 H16 C40
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:6rwm, PDBe:6rwm, PDBj:6rwm
PDBsum6rwm
PubMed32001525
UniProtE1ANT8

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