Structure of PDB 6rv6 Chain B

Receptor sequence
>6rv6B (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]
GVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTH
ICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK
FDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQ
RLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRP
CLHVPACKDPEEEELENLYF
3D structure
PDB6rv6 Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
ChainB
Resolution3.507 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC B T272 P313 T18 P59
BS02 BGC B V271 C312 V17 C58
BS03 FUC B K427 N428 K173 N174
BS04 MAN B S320 W321 S66 W67
BS05 MAN B E323 W324 E69 W70
BS06 MAN B T387 W388 T133 W134
BS07 MAN B E384 W385 R403 E130 W131 R149
BS08 MAN B G259 W260 R282 G5 W6 R28
BS09 MAN B P262 W263 P8 W9
External links
PDB RCSB:6rv6, PDBe:6rv6, PDBj:6rv6
PDBsum6rv6
PubMed31507604
UniProtP27918|PROP_HUMAN Properdin (Gene Name=CFP)

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