Structure of PDB 6rus Chain B

Receptor sequence
>6rusB (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]
GVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTH
ICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK
FDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQ
RLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRP
CLHVPACKDPEEEELENLYF
3D structure
PDB6rus Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FUC B T272 P313 T18 P59
BS02 BGC B V271 C312 V17 C58
BS03 MAN B S320 W321 R346 S66 W67 R92
BS04 MAN B E323 W324 E69 W70
BS05 MAN B W382 E440 W128 E186
BS06 MAN B T387 W388 R401 T133 W134 R147
BS07 MAN B W385 R403 W131 R149
External links
PDB RCSB:6rus, PDBe:6rus, PDBj:6rus
PDBsum6rus
PubMed31507604
UniProtP27918|PROP_HUMAN Properdin (Gene Name=CFP)

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