Structure of PDB 6rts Chain B

Receptor sequence
>6rtsB (length=508) [Search protein sequence]
AAISGTDEIRARAEQALTRCGVDLTAVKGDALTARTPLTGADLFGLRAQT
PEDVDRAVEAAHTAFLTWRTTPAPVRGALVKRFGELLTEHKQDLADLVTI
EAGKIRSEALGEVQEMIDICDFAVGLSRQLYGRTMPTERPGHRLMETWHP
LGVVGVISAFNFPVAVWAWNAAVALVCGDTVVWKPSELTPLTALACAALL
DLAIADAGAPKGLNQVVVGAADVGERLVDSPRVPLVSATGSTRMGRAVGP
RVAARFGRTILELGGNNAAVVTPSADLDLTVNAAVFAAAGTAGQRCTTLR
RLIVHEDIADTVVERLTAAFERLPIGDPFQDTTLVGPLVNEAAFGRMREA
VERATAEGGTLCAGGERQFPDAAPGAYYVRPALVRMPAQTAVVREETFAP
ILYVLTYRDLDEAIRLNNEVPQGLSAGIFTADQSEAERFLAPDGADCGIA
NVNIGTSGAEIGGAFGGEKETGGGRESGSDAWRAYMRRATNTVNYSGRVT
LAQGVDFS
3D structure
PDB6rts Structure and mechanism of piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus.
ChainB
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) N164 E265 C299 E479
Catalytic site (residue number reindexed from 1) N161 E262 C296 E476
Enzyme Commision number 1.2.1.3: aldehyde dehydrogenase (NAD(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B I160 S161 A162 F163 N164 K187 S189 G227 T242 G243 S244 M247 E265 L266 C299 E399 F401 I157 S158 A159 F160 N161 K184 S186 G224 T239 G240 S241 M244 E262 L263 C296 E396 F398
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004029 aldehyde dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

View graph for
Molecular Function
External links
PDB RCSB:6rts, PDBe:6rts, PDBj:6rts
PDBsum6rts
PubMed31793904
UniProtO85725

[Back to BioLiP]