Structure of PDB 6rtd Chain B

Receptor sequence

>6rtdB (length=466) Species: 287 (Pseudomonas aeruginosa)

APGEALYRQHCQACHGAGRLGGSGPTLLPESLSRLKPAQAREVILHGRPA
TQMAGFAGQLDDAAADALVAYLYQAPPREPQWSAEDIRASQVQPHPLATL
PSRPRFEADPLNLFVVVESGDHHVTILDGDRFEPIARFPSRYALHGGPKF
SPDGRLVYFASRDGWVTLYDLYNLKVVAEVRAGLNTRNLAVSDDGRWVLV
GNYLPGNLVLLDARDLSLVQVIPAADAQGQASRVSAVYTAPPRHSFVVAL
KDVHELWELPYANGKPVAPKRLAVADYLDDFSFSPDYRYLLGSSRQARGG
EVIELDSGARVASIPLSGMPHLGSGIYWKRDGRWVFATPNISRGVISVID
LQNWKPLKEIVTDGPGFFMRSHADSPYAWTDTFLGKKHDEILLIDKQTLE
IAHRLRPSPGKVAGHVEFTRDGRYALLSVWDRDGALVVYDAHSLEEVKRL
PMNKPSGKYNVGNKIG

3D structure

• PDB: 6rtd Crystal Structure of Dihydro-Heme d1Dehydrogenase NirN from Pseudomonas aeruginosa Reveals Amino Acid Residues Essential for Catalysis.
• Chain: B
• Resolution: 2.36 Å

Enzymatic activity

• Enzyme Commision number: 1.3.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BU3	B	W199 D214	W197 D212
BS02	DHE	B	H147 G148 G149 K151 R164 R189 N190 H323 F369 F370 R372 H417 Y461	H145 G146 G147 K149 R162 R187 N188 H321 F367 F368 R370 H415 Y459
BS03	HEC	B	H12 C13 C16 H17 P27 L29 I46 R50 T53 Q54 M55 F58 Y144	H10 C11 C14 H15 P25 L27 I44 R48 T51 Q52 M53 F56 Y142

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006783 heme biosynthetic process

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:6rtd, PDBe:6rtd, PDBj:6rtd
• PDBsum: 6rtd
• PubMed: 31173777
• UniProt: Q9I609|NIRN_PSEAE Dihydro-heme d1 dehydrogenase (Gene Name=nirN)