Structure of PDB 6rrp Chain B

Receptor sequence
>6rrpB (length=450) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
PQTPDEASLDLAATDGIRLGDRLRGLWDLRLVGGDAELPGLPREGLQLVL
DVAPKGRGLIGYLDTPERLLAAEPPRFRVLGDLLGASSASIRWRLVDQAS
GSVAPTHDCSAVFDDGTLSGRIQRLERSEDFRFVAVKRHFPLAHERIVLN
EKLLGWLVSPQHRLFHQLWHASRDKWHRLSEKQRNALRGVGWQPGPLDRE
RDARGPRKDRNASGIDFFFMHRHMLHTARSMQDLPSWERLPRPVVPLEYD
RPGFIRYFDNPDGFSVPPAWVAVDDDEYSEWLHGLKSAEAYHANFLVWES
QYQDPAYLAKLTLGQFGSELELGMHDWLHMRWASVTTDRFPADFAPRWFR
PENDFLGDPFSSHVNPVFWSFHGWIDDRIEDWYRAHERFHPGEVQRREVE
GIQWFAPGRWVEVGDPWLGPATHGLDVETMKLALRIIFSRPWYARNLKLA
3D structure
PDB6rrp A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 URS B R53 W320 V321 S329 E330 H333 R18 W270 V271 S279 E280 H283 MOAD: ic50=174.4uM
BS02 CU B H216 H220 H271 H166 H170 H221
BS03 CU B H375 H379 H432 H325 H329 H372
Gene Ontology
Molecular Function
GO:0004503 tyrosinase activity
GO:0046872 metal ion binding
Biological Process
GO:0002049 pyoverdine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6rrp, PDBe:6rrp, PDBj:6rrp
PDBsum6rrp
PubMed31899238
UniProtQ9I188

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