Structure of PDB 6rq7 Chain B

Receptor sequence
>6rq7B (length=479) Species: 9606 (Homo sapiens) [Search protein sequence]
STQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTL
PECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDV
GFLPPFLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKPVTQYLKAFSSY
QKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGC
CEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNK
DDRPKDLEGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLR
IVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNL
GKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVD
NLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPP
PFSELQRKTDRFLVNLVKLKHELTDEELQ
3D structure
PDB6rq7 Controlled dehydration, structural flexibility and gadolinium MRI contrast compound binding in the human plasma glycoprotein afamin.
ChainB
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DO3 B N295 N297 N247 N249
BS02 DO3 B Y198 I221 I294 I346 N452 Y150 I173 I246 I295 N401
BS03 DO3 B D358 F484 D307 F433
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008431 vitamin E binding
Biological Process
GO:0015031 protein transport
GO:0050821 protein stabilization
GO:0051180 vitamin transport
GO:0071693 protein transport within extracellular region
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rq7, PDBe:6rq7, PDBj:6rq7
PDBsum6rq7
PubMed31793901
UniProtP43652|AFAM_HUMAN Afamin (Gene Name=AFM)

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