Structure of PDB 6rjr Chain B

Receptor sequence
>6rjrB (length=501) Species: 28985 (Kluyveromyces lactis) [Search protein sequence]
GHPTNTADVRKDRVVTNSQGAPINEPFATQRVGQHGPLLLQDFNLLDSLA
HFNRERIPERNPHAHGSGAFGYLEITDDITDVCGSAMFDTVGKRTRCLVR
FSTVGGEKGSADTARDPRGFAIKFYSEEGNVDWVNNNTPVFFIRDPSKFP
HFIHTQKRNPETNMKDADMFWDFLTTEENQVAIHQVMILFSDRGTPASYR
NMNSYSGHTYKWSNKQGEWRYVQVHLKTDQGIKNLNNEEATKLAGENPDY
CQKDLFENIAKGNYPSWTLYIQTMTEEEAEKLPFSVFDLTKVWPHKQFPL
RRVGKMVLNENPENYFAQVEQAAFSPSHTVPYQEASADPVLQARLFSYPD
AHRYRLGPNYSQIPVNCPYASKVFNPAIRDGPMNVNGNLGKEPNYLSTSK
KYQFIQQSKPIQQHQEVWSGPAMPVHWATSPGDIDFVQARDLYNKVLSKQ
PGQQKALAHNVAVHVASACPEIQDRVFAMFARVDRGLSENIKKEALSLSP
R
3D structure
PDB6rjr Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes.
ChainB
Resolution1.895 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.11.1.6: catalase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM B N62 H64 R101 V135 N137 P147 F150 F325 V341 R345 Y349 A352 H353 R356 N61 H63 R100 V134 N136 P146 F149 F324 V340 R344 Y348 A351 H352 R355
BS02 NDP B P140 H185 R194 K228 V293 H296 V447 Q451 P139 H184 R193 K227 V292 H295 V446 Q450
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042542 response to hydrogen peroxide
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005777 peroxisome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rjr, PDBe:6rjr, PDBj:6rjr
PDBsum6rjr
PubMed31238127
UniProtQ6CR58

[Back to BioLiP]