Structure of PDB 6rb7 Chain B

Receptor sequence
>6rb7B (length=305) Species: 411470 (Mediterraneibacter gnavus ATCC 29149) [Search protein sequence]
MRNLEKYKGVIPAFYACYDKEGNISPEGVQGLTKYFVKKGVKGVYVNGSS
GECIYQSVEDRKIVLENVMKVAEGKLTVIAHVACNNTKDSQELARHAEGL
GVDAIAAIPPIYFHLPEYAIAQYWNAISAAAPNTDFVIYNIPQLAGVALT
QNLFVEMRKNPNVIGVANSSMPVQDIQMFKQAAGAEYIIFNGPDEQFMSG
RVIGAEGAIGGTYGAMPELYLKLDECINAGKMTEARKIQYACNEIIYKMC
SAHGNMYAVIKAILKINEGLELGAVREPLPALVDEDMEIVKEAAQMICDA
KKKFL
3D structure
PDB6rb7 Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
ChainB
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S49 Y112 Y139 L144 A167 I209
Catalytic site (residue number reindexed from 1) S49 Y112 Y139 L144 A167 I209
Enzyme Commision number 4.1.3.3: N-acetylneuraminate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B N255 P280 N255 P280
Gene Ontology
Molecular Function
GO:0008747 N-acetylneuraminate lyase activity
GO:0016829 lyase activity
Biological Process
GO:0019262 N-acetylneuraminate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rb7, PDBe:6rb7, PDBj:6rb7
PDBsum6rb7
PubMed31636419
UniProtA7B555|NANA_MEDG7 N-acetylneuraminate lyase (Gene Name=nanA)

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