Structure of PDB 6r79 Chain B

Receptor sequence
>6r79B (length=218) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
LPDLKIEKLEEGVFVHTSFEEVNGVVTKHGLVVLVNTDAYLIDTPFTATD
TEKLVNWFVERGYEIKGTISSHFHSDSTGGIEWLNSQSIPTYASELTNEL
LKKSGKVQAKYSFSEVSYWLVKNKIEVFYPGPGHTQDNLVVWLPESKILF
GGCFIKPHGLGNLGDANLEAWPKSAKILMSKYGKAKLVVSSHSEKGDASL
MKRTWEQALKGLKESKKT
3D structure
PDB6r79 Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase.
ChainB
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H77 H79 D81 H139 C158 K161 N167 H197
Catalytic site (residue number reindexed from 1) H72 H74 D76 H134 C153 K156 N162 H192
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H77 H79 H139 H72 H74 H134
BS02 ZN B D81 C158 H197 D76 C153 H192
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process
GO:0046677 response to antibiotic
Cellular Component
GO:0042597 periplasmic space

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Molecular Function
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Cellular Component
External links
PDB RCSB:6r79, PDBe:6r79, PDBj:6r79
PDBsum6r79
PubMed32205343
UniProtQ7WYA8|BLAB_PSEAI Metallo-beta-lactamase type 2 (Gene Name=bla-imp13)

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